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Surgery: Hereditary Multiple Exostoses (HME)

Hereditary multiple exostoses management: selective surgery, deformity correction. Dr. Priano, Milan.

Complex surgical management for hereditary condition

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Surgical Techniques

Selective Exostosis Removal

Removal of symptomatic or risky lesions, preserving others. Often staged procedures over years.

When it is used

Painful lesions, deforming lesions, compressive lesions, or lesions with suspicious growth.

Recovery

Variable based on location and number of lesions treated.

Corrective Osteotomies

Correction of secondary deformities, particularly forearm (radial-ulnar dislocation) and knee.

When it is used

Progressive deformities with functional limitation.

Recovery

Immobilization for 4-6 weeks. Physical therapy.

Postoperative Overview

HME management is multifactorial and requires a long-term approach. The goal is preserving function while intervening only when necessary. Complex cases are managed within a multidisciplinary specialist pathway at the Gaetano Pini Institute.

Recovery Pathway (indicative)

Note: This is an indicative pathway, personalised after surgery. Some elements are relatively stable (goal of the procedure, approximate hospital stay, presence of a cast or brace); others depend on the individual case (weight bearing, range of motion, imaging, sport, hardware removal, follow-up intervals) and on the surgical technique chosen.

  1. Hospital stay

    Variable: day-surgery for single lesion, 1-2 nights for osteotomies.

  2. First weeks

    Dependent on procedure type and location. Detailed protocol provided for each surgery.

  3. Second month

    Progressive rehabilitation. Follow-up imaging.

  4. Third month

    Return to activities based on specific procedure. Some deformity corrections require longer rehabilitation.

  5. Return to sport

    Individualized. Generally sports allowed once healed, with possible limitations for contact sports.

  6. Follow-up

    Long-term follow-up essential in HME: every 6-12 months throughout growth. Monitor for new symptomatic lesions and malignant transformation.

Possible Complications

Recurrence of individual lesions, progression of deformities, rare malignant transformation (1-5% lifetime risk - requires vigilance).

For parents

Hereditary Multiple Exostoses (HME): condition information page

Causes, diagnosis, conservative options and when surgery is considered.

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